Sharon L. R. Kardia

Sharon L. R. Kardia, photograph
Co-Investigator, Health and Retirement Study

Contact Information

1827 SPH I
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Email: skardia@umich.edu

Education

University of Michigan, Ph.D. Human Genetics, 1991
University of Michigan, M.A. Statistics, 1990
Carnegie-Mellon University, B.S. Biological Sciences, 1985

Research and Projects

Dr. Kardia's main research interests are in the genetic epidemiology of common chronic diseases and their risk factors. She is particularly interested in gene-environment and gene-gene interactions and in developing novel analytical strategies to understand the complex relationship between genetic variation, environmental variation, and risk of common chronic diseases. Her research utilizes genomic, epigenomic, transcriptomic, and proteomic measures on large epidemiological cohorts.

Selected Recent Publications

Ware EB, Schmitz LL, Faul JD, et al. Heterogeneity in polygenic scores for common human traits. bioRxiv. Forthcoming. doi:10.1101/106062.
Turcot V, Lu Y, Highland HM, et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet. 2018;50(1):26-41. doi:10.1038/s41588-017-0011-x.
http://www.ncbi.nlm.nih.gov/pubmed/29273807?dopt=Abstract
Marouli E, Graff M, Medina-Gomez C, et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017;542(7640):186-190. doi:10.1038/nature21039.
http://www.ncbi.nlm.nih.gov/pubmed/28146470?dopt=Abstract
Ben-Avraham D, Karasik D, Verghese J, et al. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017;9(1):209-246. doi:10.18632/aging.101151.
http://www.ncbi.nlm.nih.gov/pubmed/28077804?dopt=Abstract
Zhao W, Ware EB, He Z, Kardia SLR, Faul JD. Interaction between Social/Psychosocial Factors and Genetic Variants on Body Mass Index: A Gene-Environment Interaction Analysis in a Longitudinal Setting. International Journal of Environmental Research and Public Health. 2017;14(10):1153. doi:10.3390/ijerph14101153.