@article {10.1093/geronb/gbz156, title = {Mortality and Obesity among US Older Adults: The Role of Polygenic Risk}, journal = {The Journals of Gerontology, Series B}, volume = {76}, year = {2021}, pages = {343-347}, abstract = {To examine the relationship between obesity and mortality as a function of polygenic risk for obesity among older US adults.Using data from the 1994-2014 Health and Retirement Study in conjunction with genome-wide data, we evaluated the risk of mortality as a function of obesity classification, an individual{\textquoteright}s polygenic risk score (PGS) for obesity, and their interaction, stratified by sex. We conducted our analyses using cox proportional hazard models.Among those with an average PGS for obesity (8,143 [68.8 \%]), obese I (HR = 0.7}, keywords = {Mortality, Obesity, polygenic risk, Polygenic risk score}, issn = {1079-5014}, doi = {10.1093/geronb/gbz156}, author = {Vinneau, Justin M and Huibregtse, Brooke M and Laidley, Thomas M and Joshua A Goode and Jason D Boardman} }