@inbook {12775,
	title = {Appendix A Quantifying the Potential Health and Economic Impacts of Increased Trial Diversity},
	booktitle = { Improving Representation in Clinical Trials and Research: Building Research Equity for Women and Underrepresented Groups.},
	year = {2022},
	publisher = {National Academies Press (US)},
	organization = {National Academies Press (US)},
	address = {Washington, D.C. },
	abstract = {Chronic illness decreases quantity of life, quality of life, and years spent in the labor force. Less appreciated is the potential for differential impact of disease for different race/ethnicity-gender groups. In other words, while chronic illness affects outcomes for all groups, some groups might experience a larger impact. The goal in this analysis is to quantify the differential impact of chronic illness for groups that have historically been underrepresented in clinical trials, as clinical trials are a potential way to identify approaches to reduce these disparities. We examine three key outcomes: quantity of life (measured by life expectancy), quality of life (measured by disability-free life), and working life (measured by years in the labor force). The thought experiment considers a hypothetical world where the differential impact is eliminated, that is, that all groups share the same impact of chronic illness.},
	keywords = {Chronic illness, Future Elderly Model, gender, labor force, Quality of Life, Race/ethnicity},
	url = {https://www.ncbi.nlm.nih.gov/books/NBK584406/},
	author = {Tysinger, Bryan and Bibbins-Domingo, K. and Helman, A.}
}
