TY - JOUR T1 - The role of Hope in subsequent health and well-being for older adults: An outcome-wide longitudinal approach JF - Global Epidemiology Y1 - 2020 A1 - Long, Katelyn N.G. A1 - Eric S Kim A1 - Chen, Ying A1 - Wilson, Matthew F. A1 - Worthington Jr., Everett L. A1 - Tyler J VanderWeele KW - Hope KW - hopelessness KW - Older Adults KW - outcome-wide analysis KW - Physical Health KW - Well-being AB - Hope is a topic widely discussed in the humanities and researched in the field of psychology. To explore the potential public health implications of hope for subsequent health and well-being outcomes, we prospectively examined the relation between baseline hope and a wide range of outcomes that included indicators of: physical health, health behaviors, and psychosocial well-being in older adults using an outcome-wide approach. Data from the Health and Retirement Study (N = 12,998, mean age = 66 years) were analyzed. Bonferroni correction was used to account for multiple testing. All models controlled for a wide array of factors including: sociodemographic characteristics, personality factors, and prior values of the exposure (hope) and all outcomes. A greater sense of hope was associated with: better physical health and health behavior outcomes on some indicators (e.g., reduced risk of all cause-mortality, fewer number of chronic conditions, lower risk of cancer, and fewer sleep problems), higher psychological well-being (e.g., increased positive affect, life satisfaction, and purpose in life), lower psychological distress, and better social well-being. A secondary analysis explored antecedents of hope. We identified several potentially modifiable factors that may lead to increased hope. These results may have important population-level implications for increasing hope and improving the physical, psychological, and social well-being of our growing older adult population. VL - 2 ER -