TY - JOUR T1 - Functional limitations and health care resource utilization for individuals with cognitive impairment without dementia: Findings from a United States population-based survey. JF - Alzheimer's & Dementia Y1 - 2017 A1 - J. Scott Andrews A1 - Desai, Urvi A1 - Noam Y Kirson A1 - Caroline J. Enloe A1 - Ristovska, Ljubica A1 - King, Sarah A1 - Howard G. Birnbaum A1 - Adam S. Fleisher A1 - Ye, Wenyu A1 - Kahle-Wrobleski, Kristin KW - CIND KW - Cognitive Ability KW - Functional limitations KW - Older Adults AB -

INTRODUCTION: Little is known about functional limitations and health care resource utilization of people with cognitive impairment with no dementia (CIND).

METHODS: Respondents with stable or progressive cognitive impairment (CI) after the first (index) indication of CIND in 2000-2010 were identified from the Health and Retirement Study (HRS). Respondents never exhibiting CI were identified as potential controls. Propensity score-based optimal matching was used to adjust for differences in demographics and history of stroke. Differences between cohorts were assessed accounting for HRS survey design.

RESULTS: After matching, CIND respondents had more functional limitations (difficulty with ≥1 activities of daily living: 24% vs. 15%; ≥1 instrumental activities of daily living: 20% vs. 11%) and hospital stays (37% vs. 27%) than respondents with no CI (all P < .001). Seventy five percent of CIND respondents developed dementia in the observable follow-up (median time: ∼6 years).

DISCUSSION: Even before dementia onset, CI is associated with increased likelihood of functional limitations and greater health care resource use.

VL - 6 ER -