%0 Journal Article %J Aging Clinical and Experimental Research %D 2020 %T Patient-reported measures of well-being in older multiple myeloma patients: use of secondary data source %A Irena Cenzer %A Karin Berger %A Rodriguez, A.M. %A Ostermann, H. %A Kenneth E Covinsky %X Background: Changes in well-being of patients with multiple myeloma (MM) before and after diagnosis have not been quantified. Aims: Explore the use of secondary data to examine the changes in the well-being of older patients with MM. Methods: We used the Health and Retirement Study (HRS), linked to Medicare claims to identify older MM patients. We compared patient-reported measures (PRM), including physical impairment, sensory impairment, and patient experience (significant pain, self-rated health, depression) in the interviews before and after MM diagnosis using McNemar’s test. We propensity-matched each MM patient to five HRS participants without MM diagnosis based on baseline characteristics. We compared the change in PRM between the MM patients and their matches. Results: We identified 92 HRS patients with MM diagnosis (mean age = 74.6, SD = 8.4). Among the surviving patients, there was a decline in well-being across most measures, including ADL difficulty (23% to 40%, p value = 0.016), poor or fair self-rated health (38% to 61%, p value = 0.004), and depression (15% to 30%, p value = 0.021). Surviving patients reported worse health than participants without MM across most measures, including ADL difficulty (40% vs. 27%, p value = 0.04), significant pain (38% vs. 22%, p value = 0.01), and depression (29% vs. 11%, p value = 0.003). Discussion: Secondary data were used to identify patients with MM diagnosis, and examine changes across multiple measures of well-being. MM diagnosis negatively affects several aspects of patients’ well-being, and these declines are larger than those experienced by similar participants without MM. Conclusion: The results of this study are valuable addition to understanding the experience of patients with MM, despite several data limitations. © 2020, The Author(s). %B Aging Clinical and Experimental Research %G eng %R 10.1007/s40520-019-01465-3