Genetic Data Consortia

HRS participates in a number of genetic data consortia. The published results of these collaborations are listed below, with links to the HRS Bibliography. Several projects are still in progress, and will be added to this page upon publication.

CHARGE

Cohorts for Heart and Aging Research in Genetic Epidemiology

Website: http://www.chargeconsortium.com/

Publications from the HRS Bibliography

Barban N, Jansen R, de Vlaming R, et al. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet. 2016;48(12):1462-1472. doi:10.1038/ng.3698.
http://www.ncbi.nlm.nih.gov/pubmed/27798627?dopt=Abstract
Broer L, Aron S. Buchman, Deelen J, Smith JA, et al. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 2015;70(1):110-8. doi:10.1093/gerona/glu166.
Marouli E, Graff M, Medina-Gomez C, et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017;542(7640):186-190. doi:10.1038/nature21039.
http://www.ncbi.nlm.nih.gov/pubmed/28146470?dopt=Abstract
Pattaro C, Teumer A, Gorski M, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016;7:10023. doi:10.1038/ncomms10023.
http://www.ncbi.nlm.nih.gov/pubmed/26831199?dopt=Abstract

COGENT

Continental Origins and Genetic Epidemiology Network

Publications from the HRS Bibliography

GIANT

Genetic Investigation of Anthropometric Traits

Website: http://portals.broadinstitute.org/collaboration/giant/index.php/GIANT_co...

Publications from the HRS Bibliography

Locke AE, Kahali B, Berndt SI, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206. doi:10.1038/nature14177.
http://www.ncbi.nlm.nih.gov/pubmed/25673413?dopt=Abstract

ReproGen

Reproductive Genetics Consortium

Website: http://www.reprogen.org/

Publications from the HRS Bibliography

ROHGen

Runs of Homozygosity Genetics Consortium

Publications from the HRS Bibliography

Joshi PK, Esko T, Mattsson H, et al. Directional dominance on stature and cognition in diverse human populations. Nature. 2015;523(7561):459-62. doi:10.1038/nature14618.
http://www.ncbi.nlm.nih.gov/pubmed/26131930?dopt=Abstract

SiGN

Stroke Genetics Network

Publications from the HRS Bibliography

SSGAC

Social Science Genetics Association Consortium

Website: http://www.thessgac.org/

Publications from the HRS Bibliography

Okbay A, Jonathan P. Beauchamp, Fontana MA, Chen G-B, et al. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 2016;533(7604):539-42. doi:10.1038/nature17671.
http://www.ncbi.nlm.nih.gov/pubmed/27225129?dopt=Abstract