Co-Investigator, Health and Retirement Study
Contact Information
515 Delaware Street SE, Room 1-136 Moos Tower
MMC 609
Minneapolis, MN 55455
Phone: 612-624-1257
E-mail: [email protected]
Education
Ph.D., University of Minnesota, Minneapolis, 2004
M.P.H., University of Minnesota, Minneapolis, 2000
M.B.B.S., Grant Medical College, 1998
Research and Projects
Dr. Thyagarajan is director of the Division of Molecular Pathology and Genomics, and a faculty investigator in the Advanced Research and Diagnostic Laboratory (ARDL). The MDL processes some 25,000 specimens annually related to inherited and infectious diseases, bone marrow engraftment, and blood and solid tumor malignancies. Thyagarajan and his MDL colleagues are implementing next-generation DNA sequencing (NGS) for diagnosing genetic disease.
Selected Recent Publications
Crimmins EM, Thyagarajan B, Levine ME, Weir DR, Faul J. Associations of Age, Sex, Race/Ethnicity and Education with 13 Epigenetic Clocks in a Nationally Representative US Sample: The Health and Retirement Study. The Journals of Gerontology: Series A . 2021;76(6):1117-1123. doi:10.1093/gerona/glab016
Wu Q, Klopack ET, Kim JK, et al. Gene expression composite scores of cellular senescence predict aging health outcomes in the Health and Retirement Study. Nat Commun. 2025;16(1):9044. doi:10.1038/s41467-025-64835-8
Klopack ET, Farina MP, Thyagarajan B, Faul J, Crimmins EM. How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study. J Alzheimers Dis. 2025;106(1):54-68. doi:10.1177/13872877251338063
Wang S, Prizment A, Moshele P, et al. Aging measures and cancer in the Health and Retirement Study (HRS). Nat Commun. 2025;16(1):5916. doi:10.1038/s41467-025-60913-z
Wu Q, Klopack E, Kim JK, et al. RNA-based Indicators of Cellular Senescence Predict Aging Health Outcomes in the Health and Retirement Study. 2024. doi:10.21203/rs.3.rs-5392573/v1