Bayesian variable selection in linear quantile mixed models for longitudinal data with application to macular degeneration.
| Year of Publication |
2020
|
|---|---|
| Author | |
| Journal |
PLoS One
|
| Volume |
15
|
| Issue |
10
|
| Number of Pages |
e0241197
|
| ISSN Number |
1932-6203
|
| Abstract |
This paper presents a Bayesian analysis of linear mixed models for quantile regression based on a Cholesky decomposition for the covariance matrix of random effects. We develop a Bayesian shrinkage approach to quantile mixed regression models using a Bayesian adaptive lasso and an extended Bayesian adaptive group lasso. We also consider variable selection procedures for both fixed and random effects in a linear quantile mixed model via the Bayesian adaptive lasso and extended Bayesian adaptive group lasso with spike and slab priors. To improve mixing of the Markov chains, a simple and efficient partially collapsed Gibbs sampling algorithm is developed for posterior inference. Simulation experiments and an application to the Age-Related Macular Degeneration Trial data to demonstrate the proposed methods. |
| DOI |
10.1371/journal.pone.0241197
|
| PMID |
33104698
|
| PMCID |
PMC7588124
|
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