The association between Body Roundness Index and epigenetic aging: insights from the Health and Retirement Study

Year of Publication
2026
Author
Sihan Chen
Bo Chen
Biao Ran
Shibo Jian
Jie Chen
Jingxing Bai
Yin Huang
Zeyu Chen
Qiang Wei
Qiang Dong
Dehong Cao
Liangren Liu
Journal
Research Square
Abstract

The Body Roundness Index (BRI) has been proved to be associated with several metabolic and age-related disorders, with epigenetic pathways potentially underlying these connections. We analyzed data from the Health and Retirement Database to investigate whether higher BRI is linked to epigenetic aging.
DOI
https://doi.org/10.21203/rs.3.rs-9587275/v1
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