Sharon L. R. Kardia

Sharon L. R. Kardia
Co-Investigator, Health and Retirement Study

Contact Information

1827 SPH I
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Email: [email protected]

Education

University of Michigan, Ph.D. Human Genetics, 1991
University of Michigan, M.A. Statistics, 1990
Carnegie-Mellon University, B.S. Biological Sciences, 1985

Research and Projects

Dr. Kardia's main research interests are in the genetic epidemiology of common chronic diseases and their risk factors. She is particularly interested in gene-environment and gene-gene interactions and in developing novel analytical strategies to understand the complex relationship between genetic variation, environmental variation, and risk of common chronic diseases. Her research utilizes genomic, epigenomic, transcriptomic, and proteomic measures on large epidemiological cohorts.

Selected Recent Publications

Ware EB, Schmitz LL, Faul J, et al. Heterogeneity in polygenic scores for common human traits. bioRxiv. Forthcoming. doi:10.1101/106062
Lin L, Zhao W, Li Z, et al. Poly-epigenetic scores for cardiometabolic risk factors interact with demographic factors and health behaviors in older US Adults. Epigenetics. 2025;20(1):2469205. doi:10.1080/15592294.2025.2469205
https://www.ncbi.nlm.nih.gov/pubmed/39976511?dopt=Abstract
Bui H, Keshawarz A, Wang M, et al. Association analysis between an epigenetic alcohol risk score and blood pressure. Clin Epigenetics. 2024;16(1):149. doi:10.1186/s13148-024-01753-4
Stoldt M, Ammous F, Lin L, et al. DNA Methylation at CRP-Associated CpG Sites May Mediate the Pathway between Educational Attainment and Cognition. J Gerontol A Biol Sci Med Sci. 2024. doi:10.1093/gerona/glae159
http://www.ncbi.nlm.nih.gov/pubmed/38896024?dopt=Abstract