Title | The Associations of Pulse Pressure and Mean Arterial Pressure on Physical Function in Older Americans. |
Publication Type | Journal Article |
Year of Publication | 2023 |
Authors | Pleiss, A, Jurivich, D, Dahl, L, McGrath, B, Kin, D, McGrath, R |
Journal | Geriatrics (Basel) |
Volume | 8 |
Issue | 2 |
ISSN Number | 2308-3417 |
Keywords | mean arterial pressure, Older Americans, pulse pressure |
Abstract | BACKGROUND: We sought to examine the associations of pulse pressure (PP) and mean arterial pressure (MAP) on physical function in older Americans. METHODS: Our analytic sample included 10,478 adults aged ≥65 years from the 2006-2016 Health and Retirement Study. Handgrip strength, gait speed, and standing balance were collected using relatively standard protocols. PP and MAP were calculated from blood pressure measurements. RESULTS: Older Americans with any abnormality in PP had 1.15 (95% confidence interval (CI): 1.05-1.25) greater odds for slowness and 1.14 (CI: 1.05-1.24) greater odds for poorer standing balance. Persons with any abnormality in MAP had 0.90 (CI: 0.82-0.98) decreased odds for weakness and 1.10 (CI: 1.01-1.20) greater odds for poorer standing balance. Those with low PP had 1.19 (CI: 1.03-1.36) greater odds for slow gait speed, while persons with low MAP had 1.50 (CI: 1.09-2.05) greater odds for weakness and 1.45 (CI: 1.03-2.04) greater odds for slowness. Older Americans with high PP had 1.13 (CI: 1.03-1.25) greater odds for slowness and 1.21 (CI: 1.10-1.32) greater odds for poorer balance, whereas those with high MAP had 0.87 (CI: 0.80-0.95) decreased odds for weakness. CONCLUSIONS: Cardiovascular dysfunction, as observed by PP and MAP, may help to explain some of our findings. |
DOI | 10.3390/geriatrics8020040 |
Citation Key | 13236 |
PubMed ID | 37102966 |
PubMed Central ID | PMC10137340 |