Links Between Biomarkers and Mortality

TitleLinks Between Biomarkers and Mortality
Publication TypeBook Chapter
Year of Publication2011
AuthorsCrimmins, EM, Vasunilashorn, S
EditorRogers, RG, Crimmins, EM
Book TitleInternational Handbook of Adult Mortality
ISBN Number978-90-481-9995-2
Accession NumberWOS:000288355700018
KeywordsDemographics, Health Conditions and Status, Healthcare

A biomarker is an objectively measured indicator of a physiological state. Biomarkers include indicators of genotype, normal biological processes, pathogenic processes, and pharmacologic responses to a therapeutic intervention (Biomarkers Definitions Working Group 2001; National Heart Lung and Blood Institute 2007). Biomarkers can serve as objective indicators of health status within a sample, indicators of health change over time, and, with comparable measurement, indicators of differences across populations. They signal disease status, early physiological dysregulation preceding disease, or change in organ reserve or functioning. And they can clarify how the social, psychological, and behavioral factors traditionally examined in social science research get under the skin to influence biology and subsequent health outcomes (Crimmins and Seeman 2001, 2004; Crimmins et al. 2008a; Seeman and Crimmins 2001).


Times Cited: 2

Endnote Keywords

biomarkers/health Status/population Dynamics/therapeutic intervention/MORBIDITY

Endnote ID


Short TitleLinks Between Biomarkers and Mortality
Citation Key5246