|Title||Social Inequalities in Inflammation: Age Variations in Older Persons.|
|Publication Type||Journal Article|
|Year of Publication||2017|
|Authors||Mitchell, UA, Aneshensel, CS|
|Journal||J Aging Health|
|Date Published||2017 Aug|
|Keywords||Age Factors, Aged, Aged, 80 and over, Biomarkers, C-reactive protein, Female, Health Status Disparities, Humans, Inflammation, Male, Middle Aged, Racial Groups, Self Report, Socioeconomic factors|
OBJECTIVE: Systemic inflammation is an important risk factor for cardiovascular diseases and inequalities by race/ethnicity, gender, and education have been documented. However, there is incomplete knowledge as to how these disparities present across age, especially in late life. This study assesses whether differences in C-reactive protein (CRP), a marker of inflammation, are contingent on age among older persons.
METHOD: Data are from the 2006/2008 Health and Retirement Study ( n = 10,974) biomarker assessment. CRP was regressed on interactions between age and other status characteristics.
RESULTS: Racial/ethnic differences in inflammation do not vary significantly by age. However, gender and education differences are greatest at younger ages and then narrow steadily with increasing age.
DISCUSSION: There is considerable heterogeneity in how disparities in inflammation present across age and characteristics such as race/ethnicity, gender, and education. Understanding status differences in the influence of age on factors affecting late-life health is useful for health disparities research.
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|Alternate Journal||J Aging Health|
|PubMed Central ID||PMC5222881|
|Grant List||R24 AG045061 / AG / NIA NIH HHS / United States |
T32 AG000037 / AG / NIA NIH HHS / United States
T32 GM084903 / GM / NIGMS NIH HHS / United States
T32 AG033533 / AG / NIA NIH HHS / United States
P30 AG043073 / AG / NIA NIH HHS / United States