Urinary incontinence and its association with death, nursing home admission, and functional decline.

TitleUrinary incontinence and its association with death, nursing home admission, and functional decline.
Publication TypeJournal Article
Year of Publication2004
AuthorsHolroyd-Leduc, JM, Mehta, KM, Covinsky, KE
JournalJ Am Geriatr Soc
Date Published2004 May
ISSN Number0002-8614
Call Numberpubs_2004_Holroyd_etal.pdf
KeywordsActivities of Daily Living, Aged, Aged, 80 and over, Body Mass Index, Female, Follow-Up Studies, Frail Elderly, Health Status, Humans, Male, Nursing homes, Outcome Assessment, Health Care, Risk Factors, Smoking, Socioeconomic factors, Time Factors, Urinary incontinence

OBJECTIVES: To determine whether urinary incontinence (UI) is an independent predictor of death, nursing home admission, decline in activities of daily living (ADLs), or decline in instrumental activities of daily living (IADLs).

DESIGN: A population-based prospective cohort study from 1993 to 1995.

SETTING: Community-dwelling within the United States.

PARTICIPANTS: Six thousand five hundred six of the 7,447 subjects aged 70 and older in the Asset and Health Dynamics Among the Oldest Old study who had complete information on continence status and did not require a proxy interview at baseline.

MEASUREMENTS: The predictor was UI, and the outcomes were death, nursing home admission, ADL decline, and IADL decline. Potential confounders considered were comorbid conditions, baseline function, sensory impairment, cognition, depressive symptoms, body mass index, smoking and alcohol, demographics, and socioeconomic status.

RESULTS: The prevalence of UI was 14.8% (18.5% in women; 8.5% in men). At 2-year follow-up, subjects incontinent at baseline were more likely to have died (10.9% vs 8.7%; unadjusted odds ratio (OR)=1.29, 95% confidence interval (CI)=1.02-1.64), be admitted to a nursing home (4.4% vs 2.6%, OR=1.77; 95% CI=1.18-2.63), and to have declined in ADL function (13.6% vs 8.1%; OR=1.78, 95% CI=1.36-2.33) and IADL function (21.2% vs 13.8%; OR 1.69, 95% CI 1.39-2.05). However, after adjusting for confounders, UI was not an independent predictor of death (adjusted OR (AOR)= 0.90, 95% CI=0.67-1.21), nursing home admission (AOR=1.33, 95% CI=0.86-2.04), or ADL decline (AOR=1.24, 95% CI=0.92-1.68). Incontinence remained a predictor of IADL decline (AOR=1.31; 95% CI=1.05-1.63), although adjustment markedly reduced the strength of this association.

CONCLUSION: Higher levels of baseline illness severity and functional impairment appear to mediate the relationship between UI and adverse outcomes. The results suggest that, although UI appears to be a marker of frailty in community-dwelling elderly, it is not a strong independent risk factor for death, nursing home admission, or functional decline.

User Guide Notes


Endnote Keywords

Urinary Incontinence/Mortality/Nursing Homes/Activities of Daily Living

Endnote ID


Alternate JournalJ Am Geriatr Soc
Citation Key6929
PubMed ID15086650
Grant ListK02 HS00006-01 / HS / AHRQ HHS / United States
R01AG19827 / AG / NIA NIH HHS / United States
T32-AG00212-08 / AG / NIA NIH HHS / United States