Title | Long-term risk for depressive symptoms after a medical diagnosis. |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Polsky, D, Doshi, JA, Marcus, S, Oslin, D, Rothbard, A, Thomas, N, Thompson, CL |
Journal | Arch Intern Med |
Volume | 165 |
Issue | 11 |
Pagination | 1260-6 |
Date Published | 2005 Jun 13 |
ISSN Number | 0003-9926 |
Keywords | Chronic disease, Comorbidity, Depressive Disorder, Female, Humans, Male, Middle Aged, Prospective Studies, Risk, Time Factors |
Abstract | BACKGROUND: This study examines the risk of development of significant depressive symptoms after a new diagnosis of cancer, diabetes, hypertension, heart disease, arthritis, chronic lung disease, or stroke. METHODS: The study used 5 biennial waves (1992-2000) of the Health and Retirement Study to follow a sample of 8387 adults (aged 51 to 61 years and without significant depressive symptoms in 1992) from 1994 to 2000. Time-dependent Cox regression models estimated adjusted hazard ratios (HRs) for an episode of significant depressive symptoms after a new diagnosis for each of the 7 medical conditions. RESULTS: Within 2 years of initial diagnosis, subjects with cancer had the highest hazard of depressive symptoms (HR, 3.55; 95% confidence interval [CI], 2.79-4.52), followed by subjects with chronic lung disease (HR, 2.21; 95% CI, 1.64-2.79) and heart disease (HR, 1.45; 95% CI, 1.09-1.93). The hazard for depressive symptoms for most of these diseases decreased over time; however, subjects with heart disease continued to have a higher risk for depressive symptoms even 2 to 4 years and 4 to 8 years after diagnosis, and a significantly higher hazard for depressive symptoms developed for persons with arthritis 2 to 4 years after diagnosis (HR, 1.46; 95% CI, 1.11-1.92). CONCLUSION: The findings identify several high-risk patient groups who might benefit from depression screening and monitoring to improve health outcomes in this vulnerable population facing new medical illnesses. |
DOI | 10.1001/archinte.165.11.1260 |
User Guide Notes | |
Endnote Keywords | Depressive Symptoms/Disease/Diagnosis |
Endnote ID | 15050 |
Alternate Journal | Arch Intern Med |
Citation Key | 7023 |
PubMed ID | 15956005 |