Major depression and urinary incontinence in women: temporal associations in an epidemiologic sample.

TitleMajor depression and urinary incontinence in women: temporal associations in an epidemiologic sample.
Publication TypeJournal Article
Year of Publication2009
AuthorsMelville, JL, Fan, M-Y, Rau, H, Nygaard, IE, Katon, WJ
JournalAm J Obstet Gynecol
Volume201
Issue5
Pagination490.e1-7
Date Published2009 Nov
ISSN Number1097-6868
Call Numbernewpubs20091202_Melville.pdf
KeywordsDepressive Disorder, Major, Female, Humans, Longitudinal Studies, Middle Aged, Risk Factors, Time Factors, Urinary incontinence
Abstract

OBJECTIVE: To determine whether: (1) major depression is associated with increased risk for onset of urinary incontinence, and (2) urinary incontinence is associated with increased risk for onset of depression.

STUDY DESIGN: Longitudinal cohort study of female Health and Retirement Study participants completing baseline interviews at Wave 3 (1996-1997) and follow-up interviews at Waves 4-6 (1998-2003).

RESULTS: In a cohort of 5820 women with a mean age 59.3 (+/- 0.5) years, 6-year cumulative incidences of depression and incontinence were 11% and 21%, respectively. Major depression was associated with increased odds of incident incontinence (adjusted odds ratio, 1.46; 95% confidence interval, 1.08-1.97) during follow-up compared with those without major depression at baseline. Conversely, incontinence was not associated with increased odds of incident depression (adjusted odds ratio, 1.03; 95% confidence interval, 0.75-1.42) compared with those without incontinence at baseline.

CONCLUSION: Major depression predicted onset of urinary incontinence in a population-based sample of at-risk, community-dwelling women. Incontinence did not predict onset of depression.

Notes

PMID: 19716547

DOI10.1016/j.ajog.2009.05.047
User Guide Notes

http://www.ncbi.nlm.nih.gov/pubmed/19716547?dopt=Abstract

Endnote Keywords

Depression/Women/Incontinence

Endnote ID

21320

Alternate JournalAm. J. Obstet. Gynecol.
Citation Key7381
PubMed ID19716547
Grant ListK23 MH070704 / MH / NIMH NIH HHS / United States
5 K23 MH070704 / MH / NIMH NIH HHS / United States