|Title||Major depression and urinary incontinence in women: temporal associations in an epidemiologic sample.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Melville, JL, Fan, M-Y, Rau, H, Nygaard, IE, Katon, WJ|
|Journal||Am J Obstet Gynecol|
|Date Published||2009 Nov|
|Keywords||Depressive Disorder, Major, Female, Humans, Longitudinal Studies, Middle Aged, Risk Factors, Time Factors, Urinary incontinence|
OBJECTIVE: To determine whether: (1) major depression is associated with increased risk for onset of urinary incontinence, and (2) urinary incontinence is associated with increased risk for onset of depression.
STUDY DESIGN: Longitudinal cohort study of female Health and Retirement Study participants completing baseline interviews at Wave 3 (1996-1997) and follow-up interviews at Waves 4-6 (1998-2003).
RESULTS: In a cohort of 5820 women with a mean age 59.3 (+/- 0.5) years, 6-year cumulative incidences of depression and incontinence were 11% and 21%, respectively. Major depression was associated with increased odds of incident incontinence (adjusted odds ratio, 1.46; 95% confidence interval, 1.08-1.97) during follow-up compared with those without major depression at baseline. Conversely, incontinence was not associated with increased odds of incident depression (adjusted odds ratio, 1.03; 95% confidence interval, 0.75-1.42) compared with those without incontinence at baseline.
CONCLUSION: Major depression predicted onset of urinary incontinence in a population-based sample of at-risk, community-dwelling women. Incontinence did not predict onset of depression.
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|Alternate Journal||Am. J. Obstet. Gynecol.|
|Grant List||K23 MH070704 / MH / NIMH NIH HHS / United States |
5 K23 MH070704 / MH / NIMH NIH HHS / United States