Untreated poor vision: a contributing factor to late-life dementia.

TitleUntreated poor vision: a contributing factor to late-life dementia.
Publication TypeJournal Article
Year of Publication2010
AuthorsRogers, MAM, Langa, KM
JournalAm J Epidemiol
Date Published2010 Mar 15
ISSN Number1476-6256
KeywordsAged, 80 and over, Cognition Disorders, Dementia, Female, Humans, Logistic Models, Male, Medicare, Ophthalmology, Patient Acceptance of Health Care, Risk Factors, United States, Vision Disorders

Ophthalmologic abnormalities have been described in patients with dementia, but the extent to which poor vision and treatment for visual disorders affect cognitive decline is not well defined. Linked data from the Health and Retirement Study and Medicare files (1992-2005) were used to follow the experiences of 625 elderly US study participants with normal cognition at baseline. The outcome was a diagnosis of dementia, cognitively impaired but no dementia, or normal cognition. Poor vision was associated with development of dementia (P = 0.0048); individuals with very good or excellent vision at baseline had a 63% reduced risk of dementia (95% confidence interval (CI): 20, 82) over a mean follow-up period of 8.5 years. Participants with poorer vision who did not visit an ophthalmologist had a 9.5-fold increased risk of Alzheimer disease (95% CI: 2.3, 39.5) and a 5-fold increased risk of cognitively impaired but no dementia (95% CI: 1.6, 15.9). Poorer vision without a previous eye procedure increased the risk of Alzheimer disease 5-fold (95% CI: 1.5, 18.8). For Americans aged 90 years or older, 77.9% who maintained normal cognition had received at least one previous eye procedure compared with 51.7% of those with Alzheimer disease. Untreated poor vision is associated with cognitive decline, particularly Alzheimer disease.

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Endnote Keywords

Alzheimer disease/delirium/dementia/amnestic/cognitive disorders/health services research/Medicare/memory disorders/ophthalmology/vision disorders

Endnote ID


Alternate JournalAm J Epidemiol
Citation Key7466
PubMed ID20150357
PubMed Central IDPMC2842219
Grant ListR01 AG027010 / AG / NIA NIH HHS / United States
R01 AG030155 / AG / NIA NIH HHS / United States
U01 AG009740 / AG / NIA NIH HHS / United States
U01 AG09740 / AG / NIA NIH HHS / United States