Neighborhoods and chronic disease onset in later life.

TitleNeighborhoods and chronic disease onset in later life.
Publication TypeJournal Article
Year of Publication2011
AuthorsFreedman, VA, Grafova, IB, Rogowski, J
JournalAm J Public Health
Date Published2011 Jan
ISSN Number1541-0048
Call Numbernewpubs20101112_Freedman.pdf
KeywordsAged, Chronic disease, Environment Design, Factor Analysis, Statistical, Female, Health Resources, Health Status Disparities, Humans, Logistic Models, Male, Middle Aged, Poverty Areas, Residence Characteristics, Risk Factors, Small-Area Analysis, Social Environment, Social Problems, Socioeconomic factors, United States

OBJECTIVES: To strengthen existing evidence on the role of neighborhoods in chronic disease onset in later life, we investigated associations between multiple neighborhood features and 2-year onset of 6 common conditions using a national sample of older adults.

METHODS: Neighborhood features for adults aged 55 years or older in the 2002 Health and Retirement Study were measured by use of previously validated scales reflecting the built, social, and economic environment. Two-level random-intercept logistic models predicting the onset of heart problems, hypertension, stroke, diabetes, cancer, and arthritis by 2004 were estimated.

RESULTS: In adjusted models, living in more economically disadvantaged areas predicted the onset of heart problems for women (odds ratio [OR] = 1.20; P < .05). Living in more highly segregated, higher-crime areas was associated with greater chances of developing cancer for men (OR = 1.31; P < .05) and women (OR = 1.25; P < .05).

CONCLUSIONS: The neighborhood economic environment is associated with heart disease onset for women, and neighborhood-level social stressors are associated with cancer onset for men and women. The social and biological mechanisms that underlie these associations require further investigation.

User Guide Notes

Endnote Keywords

Chronic Disease/neighborhood Characteristics/Safety/crime/Heart disease/CANCER

Endnote ID


Alternate JournalAm J Public Health
Citation Key7560
PubMed ID20299643
PubMed Central IDPMC2912970
Grant ListR01 AG024058-05 / AG / NIA NIH HHS / United States
P50 ES012383-04 / ES / NIEHS NIH HHS / United States
R24 HD041028 / HD / NICHD NIH HHS / United States
R01 AG024058 / AG / NIA NIH HHS / United States
P50 ES12383 / ES / NIEHS NIH HHS / United States
P50 ES012383 / ES / NIEHS NIH HHS / United States