Current and long-term spousal caregiving and onset of cardiovascular disease.

TitleCurrent and long-term spousal caregiving and onset of cardiovascular disease.
Publication TypeJournal Article
Year of Publication2012
AuthorsCapistrant, BD, J Moon, R, Berkman, LF, M Glymour, M
JournalJ Epidemiol Community Health
Date Published2012 Oct
ISSN Number1470-2738
KeywordsActivities of Daily Living, Adult, Aged, Aged, 80 and over, Cardiovascular Diseases, Caregivers, Female, Follow-Up Studies, Humans, Incidence, Interviews as Topic, Long-term Care, Male, Middle Aged, Proportional Hazards Models, Risk Factors, Self Report, Socioeconomic factors, Spouses, Stress, Psychological, United States

<p><b>BACKGROUND: </b>Prior evidence suggests that caregiving may increase risk of cardiovascular disease (CVD) onset. This association has never been examined in a nationally (USA) representative sample, and prior studies could not fully control for socioeconomic confounders. This paper seeks to estimate the association between spousal caregiving and incident CVD in older Americans.</p><p><b>METHODS: </b>Married, CVD-free Health and Retirement Study respondents aged 50+ years (n=8472) were followed up to 8 years (1669 new stroke or heart disease diagnoses). Current caregiving exposure was defined as assisting a spouse with basic or instrumental activities of daily living ≥14 h/week according to the care recipients' report in the most recent prior biennial survey; we define providing ≥14 h/week of care at two consecutive biennial surveys as 'long-term caregiving'. Inverse probability weighted discrete-time hazard models with time-updated exposure and covariate information (including socioeconomic and cardiovascular risk factors) were used to estimate the effect of caregiving on incident CVD.</p><p><b>RESULTS: </b>Caregiving significantly predicted CVD incidence (HR=1.35, 95% CI 1.06 to 1.68) in the population overall. Long-term caregiving was associated with double the risk of CVD onset (HR=1.95, 95% CI 1.19 to 3.18). This association for long-term care givers varied significantly by race (p<0.01): caregiving predicted CVD onset for white (HR=2.37, 95% CI 1.43 to 3.92) but not for non-white (HR=0.28, 95% CI 0.06 to 1.28).</p><p><b>CONCLUSIONS: </b>Spousal caregiving independently predicted risk of CVD in a large sample of US adults. There was significant evidence that the effect for long-term care givers differs for non-whites and white.</p>


Journal of epidemiology and community health J Epidemiol Community Health. 2011 Nov 11.

User Guide Notes

Endnote Keywords

Spousal care/cardiovascular disease/Socioeconomic Differences/risk Factors/Activities Of Daily Living/IADLs

Endnote ID


Alternate JournalJ Epidemiol Community Health
Citation Key7625
PubMed ID22080816
PubMed Central IDPMC3855843
Grant ListU01 AG009740 / AG / NIA NIH HHS / United States
AG034385-01 / AG / NIA NIH HHS / United States
U01AG009740 / AG / NIA NIH HHS / United States
T32 HL098048 / HL / NHLBI NIH HHS / United States
R21 AG034385 / AG / NIA NIH HHS / United States
R24 HD050924 / HD / NICHD NIH HHS / United States
T32-HL098048-01 / HL / NHLBI NIH HHS / United States