Prevalence of cognitive impairment in older adults with heart failure.

TitlePrevalence of cognitive impairment in older adults with heart failure.
Publication TypeJournal Article
Year of Publication2012
AuthorsGure, TR, Blaum, CS, Giordani, BJ, Koelling, TM, Galecki, AT, Pressler, SJ, Hummel, SL, Langa, KM
JournalJ Am Geriatr Soc
Date Published2012 Sep
ISSN Number1532-5415
KeywordsAged, Aged, 80 and over, Algorithms, Chi-Square Distribution, Cognition Disorders, Cross-Sectional Studies, Demography, Female, Heart Failure, Humans, Logistic Models, Male, Medicare, Prevalence, United States

OBJECTIVES: To determine the prevalence of cognitive impairment in older adults with heart failure (HF).

DESIGN: Cross-sectional analysis of the 2004 wave of the nationally representative Health and Retirement Study linked to 2002 to 2004 Medicare administrative claims.

SETTING: United States, community.

PARTICIPANTS: Six thousand one hundred eighty-nine individuals aged 67 and older.

MEASUREMENTS: An algorithm was developed using a combination of self- and proxy report of a heart problem and the presence of one or more Medicare claims in administrative files using standard HF diagnostic codes. On the basis of the algorithm, three categories were created to characterize the likelihood of a HF diagnosis: high or moderate probability of HF, low probability of HF, and no HF. Cognitive function was assessed using a screening measure of cognitive function or according to proxy rating. Age-adjusted prevalence estimates of cognitive impairment were calculated for the three groups.

RESULTS: The prevalence of cognitive impairment consistent with dementia in older adults with HF was 15%, and the prevalence of mild cognitive impairment was 24%. The odds of dementia in those with HF were significantly higher, even after adjustment for age, education level, net worth, and prior stroke (odds ratio = 1.52, 95% confidence interval = 1.14-2.02).

CONCLUSION: Cognitive impairment is common in older adults with HF and is independently associated with risk of dementia. A cognitive assessment should be routinely incorporated into HF-focused models of care.

User Guide Notes

Endnote Keywords

Cognition/Cognitive impairment/Cardiovascular disease/heart Diseases/epidemiology/dementia/PREVALENCE

Endnote ID


Alternate JournalJ Am Geriatr Soc
Citation Key7761
PubMed ID22882000
PubMed Central IDPMC3445700
Grant ListU01 AG09740 / AG / NIA NIH HHS / United States
R01 AG027010-02S1 / AG / NIA NIH HHS / United States
R01 AG027010 / AG / NIA NIH HHS / United States
UL1 RR024986 / RR / NCRR NIH HHS / United States
U01 AG009740 / AG / NIA NIH HHS / United States
R01 AG030155 / AG / NIA NIH HHS / United States
P30 AG024824 / AG / NIA NIH HHS / United States
K23 HL109176 / HL / NHLBI NIH HHS / United States