Title | Clinical complexity and mortality in middle-aged and older adults with diabetes. |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Cigolle, CT, Kabeto, MU, Lee, PG, Blaum, CS |
Journal | J Gerontol A Biol Sci Med Sci |
Volume | 67 |
Issue | 12 |
Pagination | 1313-20 |
Date Published | 2012 Dec |
ISSN Number | 1758-535X |
Keywords | Activities of Daily Living, Aged, Comorbidity, Diabetes Complications, Diabetes Mellitus, Female, Health Status, Humans, Male, Middle Aged, Proportional Hazards Models, Self Care |
Abstract | BACKGROUND: Middle-aged and older adults with diabetes are heterogeneous and may be characterized as belonging to one of three clinical groups: a relatively healthy group, a group having characteristics likely to make diabetes self-management difficult, and a group with poor health status for whom current management targets have uncertain benefit. METHODS: We analyzed waves 2004-2008 of the Health and Retirement Study and the supplemental Health and Retirement Study 2003 Diabetes Study. The sample included adults with diabetes 51 years and older (n = 3,507, representing 13.6 million in 2004). We investigated the mortality outcomes for the three clinical groups, using survival analysis and Cox proportional hazard models. RESULTS: The 5-year survival probabilities were Relatively Healthy Group, 90.8%; Self-Management Difficulty Group, 79.4%; and Uncertain Benefit Group, 52.5%. For all age groups and clinical groups, except those 76 years and older in the Uncertain Benefit Group, survival exceeded 50%. CONCLUSIONS: This study reveals the substantial survival of middle-aged and older adults with diabetes, regardless of health status. These findings have implications for the clinical management of and future research about diabetes patients with multiple comorbidities. |
DOI | 10.1093/gerona/gls095 |
User Guide Notes | |
Endnote Keywords | Mortality/Diabetes Mellitus/Disease management/Physiological aspects/Prevalence/Demographic aspects/Diabetics/Health aspects/Older people |
Endnote ID | 69726 |
Alternate Journal | J Gerontol A Biol Sci Med Sci |
Citation Key | 7775 |
PubMed ID | 22492022 |
PubMed Central ID | PMC3670162 |
Grant List | P30 DK092926 / DK / NIDDK NIH HHS / United States K08 AG031837 / AG / NIA NIH HHS / United States U01 AG09740 / AG / NIA NIH HHS / United States 1R24HS019459-01 / HS / AHRQ HHS / United States 5K08AG031837 / AG / NIA NIH HHS / United States |