Clinical complexity and mortality in middle-aged and older adults with diabetes.

TitleClinical complexity and mortality in middle-aged and older adults with diabetes.
Publication TypeJournal Article
Year of Publication2012
AuthorsCigolle, CT, Kabeto, MU, Lee, PG, Blaum, CS
JournalJ Gerontol A Biol Sci Med Sci
Date Published2012 Dec
ISSN Number1758-535X
KeywordsActivities of Daily Living, Aged, Comorbidity, Diabetes Complications, Diabetes Mellitus, Female, Health Status, Humans, Male, Middle Aged, Proportional Hazards Models, Self Care

BACKGROUND: Middle-aged and older adults with diabetes are heterogeneous and may be characterized as belonging to one of three clinical groups: a relatively healthy group, a group having characteristics likely to make diabetes self-management difficult, and a group with poor health status for whom current management targets have uncertain benefit.

METHODS: We analyzed waves 2004-2008 of the Health and Retirement Study and the supplemental Health and Retirement Study 2003 Diabetes Study. The sample included adults with diabetes 51 years and older (n = 3,507, representing 13.6 million in 2004). We investigated the mortality outcomes for the three clinical groups, using survival analysis and Cox proportional hazard models.

RESULTS: The 5-year survival probabilities were Relatively Healthy Group, 90.8%; Self-Management Difficulty Group, 79.4%; and Uncertain Benefit Group, 52.5%. For all age groups and clinical groups, except those 76 years and older in the Uncertain Benefit Group, survival exceeded 50%.

CONCLUSIONS: This study reveals the substantial survival of middle-aged and older adults with diabetes, regardless of health status. These findings have implications for the clinical management of and future research about diabetes patients with multiple comorbidities.

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Endnote Keywords

Mortality/Diabetes Mellitus/Disease management/Physiological aspects/Prevalence/Demographic aspects/Diabetics/Health aspects/Older people

Endnote ID


Alternate JournalJ Gerontol A Biol Sci Med Sci
Citation Key7775
PubMed ID22492022
PubMed Central IDPMC3670162
Grant ListP30 DK092926 / DK / NIDDK NIH HHS / United States
K08 AG031837 / AG / NIA NIH HHS / United States
U01 AG09740 / AG / NIA NIH HHS / United States
1R24HS019459-01 / HS / AHRQ HHS / United States
5K08AG031837 / AG / NIA NIH HHS / United States