|Title||Functional limitations in older adults who have cognitive impairment without dementia.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Gure, TR, Langa, KM, Fisher, GG, Piette, JD, Plassman, BL|
|Journal||J Geriatr Psychiatry Neurol|
|Date Published||2013 Jun|
|Keywords||Activities of Daily Living, Age Factors, Aged, Aged, 80 and over, Cognitive Dysfunction, Dementia, Female, Humans, Male, Neuropsychological tests, Severity of Illness Index, Surveys and Questionnaires|
OBJECTIVE: To characterize the prevalence of functional limitations among older adults with cognitive impairment without dementia (CIND).
METHODS: Secondary data analysis was performed using the Aging, Demographics, and Memory Study data set. A total of 856 individuals aged ≥ 71 years were assigned to 3 diagnostic cognitive categories. A questionnaire was completed by a proxy informant regarding functional limitations for 744 of the 856 respondents.
RESULTS: Of the 744 patients, 263 (13.9%) had dementia, 201 (21.3%) had CIND, and 280 (64.8%) had normal cognition. Informants reported ≥1 instrumental activities of daily living (ADLs) limitation in 45% of the patients with CIND compared to 13% of the patients with normal cognition and 85% of the patients with dementia (P < .001). The ADL impairments among individuals with CIND were primarily attributed to physical health problems (n = 41; 40%).
CONCLUSIONS: Many individuals with CIND have impairment in a range of complex and basic daily activities, largely due to physical health problems.
NLM Title Abbreviation: J Geriatr Psychiatry Neurol
|User Guide Notes|
|Endnote Keywords|| |
ADAMS/Cognitive Impairment/ADL and IADL Impairments/Physical health/Dementia/Functional limitation
|Endnote ID|| |
|Alternate Journal||J Geriatr Psychiatry Neurol|
|PubMed Central ID||PMC3726208|
|Grant List||DK 020572 / DK / NIDDK NIH HHS / United States |
U01 AG09740 / AG / NIA NIH HHS / United States
P60 DK020572 / DK / NIDDK NIH HHS / United States
R01 AG027010-02S1 / AG / NIA NIH HHS / United States
R01 AG027010 / AG / NIA NIH HHS / United States
P30 DK020572 / DK / NIDDK NIH HHS / United States
UL1 RR024986 / RR / NCRR NIH HHS / United States
U01 AG009740 / AG / NIA NIH HHS / United States
P30 DK092926 / DK / NIDDK NIH HHS / United States
R01 AG030155 / AG / NIA NIH HHS / United States