Title | Early life predictors of atrial fibrillation-related mortality: evidence from the health and retirement study. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | M. Glymour, M, Benjamin, EJ, Kosheleva, A, Gilsanz, P, Curtis, LH, Patton, KK |
Journal | Health Place |
Volume | 21 |
Pagination | 133-9 |
Date Published | 2013 May |
ISSN Number | 1873-2054 |
Keywords | Aged, Atrial Fibrillation, Child, Geography, Medical, Humans, Middle Aged, Risk Factors, Social determinants of health, Socioeconomic factors, Southeastern United States |
Abstract | Prior research found that Americans born in 6 southeastern states (the AF-risk zone) had elevated risk of AF-related mortality, but no mechanisms were identified. We hypothesized the association between AF-related mortality and AF-risk zone birth is explained by indicators of childhood social disadvantage or adult risk factors. In 24,323 participants in the US Health and Retirement Study, we found that birth in the AF-risk zone was significantly associated with hazard of AF-related mortality. Among whites, the relationship was specific to place of birth, rather than place of adult residence. Neither paternal education nor subjectively assessed childhood SES predicted AF-related mortality. Conventional childhood and adult cardiovascular risk factors did not explain the association between place of birth and AF-related mortality. |
DOI | 10.1016/j.healthplace.2012.12.008 |
User Guide Notes | |
Endnote Keywords | Mortality/LOW-BIRTH-WEIGHT/FIRST STROKE/HEIGHT/LIFECOURSE SOCIAL CONDITIONS/CARDIOVASCULAR-DISEASE/STROKE BELT/RISK-FACTOR/Lifecourse/Public Health/occupational health/environmental health/CHILDHOOD/Atrial fibrillation/CORONARY-HEART-DISEASE/Residence |
Endnote ID | 69076 |
Alternate Journal | Health Place |
Citation Key | 7834 |
PubMed ID | 23454734 |
PubMed Central ID | PMC3640834 |
Grant List | U01 AG009740 / AG / NIA NIH HHS / United States R01 HL092577 / HL / NHLBI NIH HHS / United States RC1 HL101056 / HL / NHLBI NIH HHS / United States R01 HL102214 / HL / NHLBI NIH HHS / United States F31 HL112613 / HL / NHLBI NIH HHS / United States 1RC1-HL101056 / HL / NHLBI NIH HHS / United States 1R01AG028321 / AG / NIA NIH HHS / United States R21 AG034385 / AG / NIA NIH HHS / United States 1R01HL102214 / HL / NHLBI NIH HHS / United States 1R01HL092577 / HL / NHLBI NIH HHS / United States R01 AG028321 / AG / NIA NIH HHS / United States |