Early life predictors of atrial fibrillation-related mortality: evidence from the health and retirement study.

TitleEarly life predictors of atrial fibrillation-related mortality: evidence from the health and retirement study.
Publication TypeJournal Article
Year of Publication2013
AuthorsM. Glymour, M, Benjamin, EJ, Kosheleva, A, Gilsanz, P, Curtis, LH, Patton, KK
JournalHealth Place
Volume21
Pagination133-9
Date Published2013 May
ISSN Number1873-2054
KeywordsAged, Atrial Fibrillation, Child, Geography, Medical, Humans, Middle Aged, Risk Factors, Social determinants of health, Socioeconomic factors, Southeastern United States
Abstract

Prior research found that Americans born in 6 southeastern states (the AF-risk zone) had elevated risk of AF-related mortality, but no mechanisms were identified. We hypothesized the association between AF-related mortality and AF-risk zone birth is explained by indicators of childhood social disadvantage or adult risk factors. In 24,323 participants in the US Health and Retirement Study, we found that birth in the AF-risk zone was significantly associated with hazard of AF-related mortality. Among whites, the relationship was specific to place of birth, rather than place of adult residence. Neither paternal education nor subjectively assessed childhood SES predicted AF-related mortality. Conventional childhood and adult cardiovascular risk factors did not explain the association between place of birth and AF-related mortality.
DOI10.1016/j.healthplace.2012.12.008
User Guide Notes

http://www.ncbi.nlm.nih.gov/pubmed/23454734?dopt=Abstract
Endnote Keywords

Mortality/LOW-BIRTH-WEIGHT/FIRST STROKE/HEIGHT/LIFECOURSE SOCIAL CONDITIONS/CARDIOVASCULAR-DISEASE/STROKE BELT/RISK-FACTOR/Lifecourse/Public Health/occupational health/environmental health/CHILDHOOD/Atrial fibrillation/CORONARY-HEART-DISEASE/Residence
Endnote ID

69076
Alternate JournalHealth Place
Citation Key7834
PubMed ID23454734
PubMed Central IDPMC3640834
Grant ListU01 AG009740 / AG / NIA NIH HHS / United States
R01 HL092577 / HL / NHLBI NIH HHS / United States
RC1 HL101056 / HL / NHLBI NIH HHS / United States
R01 HL102214 / HL / NHLBI NIH HHS / United States
F31 HL112613 / HL / NHLBI NIH HHS / United States
1RC1-HL101056 / HL / NHLBI NIH HHS / United States
1R01AG028321 / AG / NIA NIH HHS / United States
R21 AG034385 / AG / NIA NIH HHS / United States
1R01HL102214 / HL / NHLBI NIH HHS / United States
1R01HL092577 / HL / NHLBI NIH HHS / United States
R01 AG028321 / AG / NIA NIH HHS / United States