Development and validation of a brief dementia screening indicator for primary care

TitleDevelopment and validation of a brief dementia screening indicator for primary care
Publication TypeJournal Article
Year of Publication2014
AuthorsBarnes, DE, Beiser, AS, Lee, A, Langa, KM, Koyama, A, Preis, SR, Neuhaus, J, McCammon, R, Yaffe, K, Seshadri, S, Haan, MN, Weir, DR
JournalAlzheimer's and Dementia
KeywordsHealth Conditions and Status, Healthcare, Risk Taking

Background: Detection of any cognitive impairment is mandated as part of the Medicare annual wellness visit, but screening all patients may result in excessive false positives. Methods: We developed and validated a brief Dementia Screening Indicator using data from four large, ongoing cohort studies (the Cardiovascular Health Study CHS ; the Framingham Heart Study FHS ; the Health and Retirement Study HRS ; the Sacramento Area Latino Study on Aging SALSA ) to help clinicians identify a subgroup of high-risk patients to target for cognitive screening. Results: The final Dementia Screening Indicator included age (1 point/year; ages, 65-79 years), less than 12 years of education (9 points), stroke (6 points), diabetes mellitus (3 points), body mass index less than 18.5 kg/m2 (8 points), requiring assistance with money or medications (10 points), and depressive symptoms (6 points). Accuracy was good across the cohorts (Harrell's C statistic: CHS, 0.68; FHS, 0.77; HRS, 0.76; SALSA, 0.78). Conclusions: The Dementia Screening Indicator is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening. 2014 The Alzheimer's Association.


Export Date: 21 April 2014 Source: Scopus Article in Press

Endnote Keywords

Dementia/Primary care/Risk prediction modeling/Screening/Cognitive Impairment

Endnote ID


Citation Key7996
PubMed ID24491321
PubMed Central IDPMC4119094