Development and validation of a brief dementia screening indicator for primary care.

TitleDevelopment and validation of a brief dementia screening indicator for primary care.
Publication TypeJournal Article
Year of Publication2014
AuthorsBarnes, DE, Beiser, AS, Lee, A, Langa, KM, Koyama, A, Preis, SR, Neuhaus, J, McCammon, RJ, Yaffe, K, Seshadri, S, Haan, MN, Weir, DR
JournalAlzheimers Dement
Volume10
Issue6
Pagination656-665.e1
Date Published2014 Nov
ISSN Number1552-5279
KeywordsAged, Cohort Studies, Dementia, Female, Humans, Male, Mass Screening, Predictive Value of Tests, Primary Health Care, Proportional Hazards Models, Risk Assessment
Abstract

BACKGROUND: Detection of "any cognitive impairment" is mandated as part of the Medicare annual wellness visit, but screening all patients may result in excessive false positives.

METHODS: We developed and validated a brief Dementia Screening Indicator using data from four large, ongoing cohort studies (the Cardiovascular Health Study [CHS]; the Framingham Heart Study [FHS]; the Health and Retirement Study [HRS]; the Sacramento Area Latino Study on Aging [SALSA]) to help clinicians identify a subgroup of high-risk patients to target for cognitive screening.

RESULTS: The final Dementia Screening Indicator included age (1 point/year; ages, 65-79 years), less than 12 years of education (9 points), stroke (6 points), diabetes mellitus (3 points), body mass index less than 18.5 kg/m(2) (8 points), requiring assistance with money or medications (10 points), and depressive symptoms (6 points). Accuracy was good across the cohorts (Harrell's C statistic: CHS, 0.68; FHS, 0.77; HRS, 0.76; SALSA, 0.78).

CONCLUSIONS: The Dementia Screening Indicator is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening.

Notes

Export Date: 21 April 2014 Source: Scopus Article in Press

URLhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84893186546andpartnerID=40andmd5=3b617dce24578e022db389d90ad9ddd1
DOI10.1016/j.jalz.2013.11.006
User Guide Notes

http://www.ncbi.nlm.nih.gov/pubmed/24491321?dopt=Abstract

Endnote Keywords

Dementia/Primary care/Risk prediction modeling/Screening/Cognitive Impairment

Endnote ID

999999

Alternate JournalAlzheimers Dement
Citation Key7996
PubMed ID24491321
PubMed Central IDPMC4119094
Grant ListN01HC85239 / HC / NHLBI NIH HHS / United States
AG12975 / AG / NIA NIH HHS / United States
AG033193 / AG / NIA NIH HHS / United States
DK60753 / DK / NIDDK NIH HHS / United States
N01HC85081 / HC / NHLBI NIH HHS / United States
R01 AG033193 / AG / NIA NIH HHS / United States
N01HC85086 / HC / NHLBI NIH HHS / United States
N01HC85082 / HC / NHLBI NIH HHS / United States
R01 AG012975 / AG / NIA NIH HHS / United States
AG081220 / AG / NIA NIH HHS / United States
NS017950 / NS / NINDS NIH HHS / United States
AG023629 / AG / NIA NIH HHS / United States
HHSN268201200036 C / / PHS HHS / United States
N01 HC55222 / HC / NHLBI NIH HHS / United States
AG033040 / AG / NIA NIH HHS / United States
N01-HC-25195 / HC / NHLBI NIH HHS / United States
AG013846 / AG / NIA NIH HHS / United States
R01 NS017950 / NS / NINDS NIH HHS / United States
K24-AG031155 / AG / NIA NIH HHS / United States
N01HC85080 / HC / NHLBI NIH HHS / United States
U01 AG009740 / AG / NIA NIH HHS / United States
N01HC85079 / HC / NHLBI NIH HHS / United States
K24 AG031155 / AG / NIA NIH HHS / United States
R01 AG008122 / AG / NIA NIH HHS / United States
HL080295 / HL / NHLBI NIH HHS / United States
N01HC85083 / HC / NHLBI NIH HHS / United States