Genetic and educational assortative mating among US adults.

TitleGenetic and educational assortative mating among US adults.
Publication TypeJournal Article
Year of Publication2014
AuthorsDomingue, BW, Fletcher, JM, Conley, DC, Boardman, JD
JournalProc Natl Acad Sci U S A
Volume111
Issue22
Pagination7996-8000
Date Published2014 Jun 03
ISSN Number1091-6490
KeywordsContinental Population Groups, Databases, Genetic, Educational Status, Ethnic Groups, Female, Genome-Wide Association Study, Genotype, Humans, Male, Marriage, Metagenomics, Phenotype, Sexual Behavior, Spouses, United States
Abstract

Understanding the social and biological mechanisms that lead to homogamy (similar individuals marrying one another) has been a long-standing issue across many fields of scientific inquiry. Using a nationally representative sample of non-Hispanic white US adults from the Health and Retirement Study and information from 1.7 million single-nucleotide polymorphisms, we compare genetic similarity among married couples to noncoupled pairs in the population. We provide evidence for genetic assortative mating in this population but the strength of this association is substantially smaller than the strength of educational assortative mating in the same sample. Furthermore, genetic similarity explains at most 10% of the assortative mating by education levels. Results are replicated using comparable data from the Framingham Heart Study.

Notes

Times Cited: 0

DOI10.1073/pnas.1321426111
User Guide Notes

http://www.ncbi.nlm.nih.gov/pubmed/24843128?dopt=Abstract

Endnote Keywords

genetic homogamy/homophily/random mating/genetics/genetics

Endnote ID

999999

Alternate JournalProc Natl Acad Sci U S A
Citation Key8110
PubMed ID24843128
PubMed Central IDPMC4050565
Grant ListRC4 AG039029 / AG / NIA NIH HHS / United States
RC4AG039029 / AG / NIA NIH HHS / United States
R24HD066613 / HD / NICHD NIH HHS / United States
R21 HD078031 / HD / NICHD NIH HHS / United States
U01 AG009740 / AG / NIA NIH HHS / United States
R21 HD071884 / HD / NICHD NIH HHS / United States
P30 AG017266 / AG / NIA NIH HHS / United States
R21HD078031 / HD / NICHD NIH HHS / United States
R24 HD066613 / HD / NICHD NIH HHS / United States
U01AG009740 / AG / NIA NIH HHS / United States
P2C HD047873 / HD / NICHD NIH HHS / United States
1R21HD071884 / HD / NICHD NIH HHS / United States
RC2 AG036495 / AG / NIA NIH HHS / United States
P2C HD066613 / HD / NICHD NIH HHS / United States
RC2AG036495 / AG / NIA NIH HHS / United States