Estimating the Cognitive Effects of Prevalent Diabetes, Recent Onset Diabetes, and the Duration of Diabetes among Older Adults

TitleEstimating the Cognitive Effects of Prevalent Diabetes, Recent Onset Diabetes, and the Duration of Diabetes among Older Adults
Publication TypeJournal Article
Year of Publication2015
AuthorsWu, Q, Tchetgen Tchetgen, EJ, Osypuk, TL, Weuve, J, White, K, Mujahid, M, Glymour, MM
JournalDementia and Geriatric Cognitive Disorders
Volume39
Issue3-4
Pagination239-249
KeywordsHealth Conditions and Status
Abstract

Background: Little evidence is available on the effects of incident diabetes or diabetes duration on cognitive aging. Methods: We evaluated the effects of prevalent and incident diabetes on deteriorations in cognitive function, based on participants (n = 8,671) aged 65 in the Health and Retirement Study in 2000. Inverse probability weighting was used to account for selective attrition and time-varying confounding of incident diabetes. Results: Prevalent diabetes predicted higher odds of dementia odds ratio 1.27; 95 confidence interval (CI) 1.03-1.58 and worse memory (-0.06 in z-score units; 95 CI -0.10 to -0.02), but incident diabetes or diabetes duration up to 8 years of follow-up was not predictive. Conclusion: Prevalent diabetes predicted lower cognition but not recent onset diabetes. (C) 2015 S. Karger AG, Basel

Notes

Times Cited: 0 0

DOI10.1159/000368654
Endnote Keywords

Diabetes/Cognitive Function/Dementia

Endnote ID

999999

Citation Key8187