Predictors of Mortality Up to 1 Year After Emergency Major Abdominal Surgery in Older Adults.

TitlePredictors of Mortality Up to 1 Year After Emergency Major Abdominal Surgery in Older Adults.
Publication TypeJournal Article
Year of Publication2015
AuthorsCooper, Z, Mitchell, SL, Gorges, RJ, Rosenthal, RA, Lipsitz, SR, Kelley, AS
JournalJ Am Geriatr Soc
Volume63
Issue12
Pagination2572-2579
Date Published2015 Dec
ISSN Number1532-5415
Abstract

OBJECTIVES: To identify factors associated with mortality in older adults 30, 180, and 365 days after emergency major abdominal surgery.

DESIGN: A retrospective study linked to Medicare claims from 2000 to 2010.

SETTING: Health and Retirement Study (HRS).

PARTICIPANTS: Medicare beneficiaries aged 65.5 enrolled in the HRS from 2000 to 2010 with at least one urgent or emergency major abdominal surgery and a core interview from the HRS within 3 years before surgery.

MEASUREMENTS: Survival analysis was used to describe all-cause mortality 30, 180, and 365 days after surgery. Complementary log-log regression was used to identify participant characteristics and postoperative events associated with poorer survival.

RESULTS: Four hundred individuals had one of the urgent or emergency surgeries of interest, 24% of whom were aged 85 and older, 50% had coronary artery disease, 48% had cancer, 33% had congestive heart failure, and 37% experienced a postoperative complication. Postoperative mortality was 20% at 30 days, 31% at 180 days, and 34% at 365 days. Of those aged 85 and older, 50% were dead 1 year after surgery. After multivariate adjustment including postoperative complications, dementia (hazard ratio (HR) = 2.02, 95% confidence interval (CI) = 1.24-3.31), hospitalization within 6 months before surgery (HR = 1.63, 95% CI = 1.12-2.28), and complications (HR = 3.45, 95% CI = 2.32-5.13) were independently associated with worse 1-year survival.

CONCLUSION: Overall mortality is high in many older adults up to 1 year after undergoing emergency major abdominal surgery. The occurrence of a complication is the clinical factor most strongly associated with worse survival.

DOI10.1111/jgs.13785
User Guide Notes

http://www.ncbi.nlm.nih.gov/pubmed/26661929?dopt=Abstract

Endnote Keywords

Mortality/surgical complications/survival analysis/geriatric surgery/emergency surgery/major abdominal surgery/Complications and side effects/Patient outcomes/Dementia/Coronary heart disease

Endnote ID

999999

Alternate JournalJ Am Geriatr Soc
Citation Key8246
PubMed ID26661929
PubMed Central IDPMC4688175
Grant ListK23 AG040774 / AG / NIA NIH HHS / United States
K24 AG033640 / AG / NIA NIH HHS / United States
R03 AG042361 / AG / NIA NIH HHS / United States