|Title||Adherence to diabetes guidelines for screening, physical activity and medication and onset of complications and death.|
|Publication Type||Journal Article|
|Year of Publication||2015|
|Authors||Chen, Y, Sloan, FA, Yashkin, A|
|Journal||J Diabetes Complications|
|Date Published||2015 Nov-Dec|
|Keywords||Aged, Aged, 80 and over, Combined Modality Therapy, Diabetes Complications, Diabetes Mellitus, Early Diagnosis, Female, Health Promotion, Health Surveys, Humans, Hypoglycemic Agents, Longitudinal Studies, Male, Mass Screening, Medicare Part A, Medicare Part B, Medication Adherence, Motor Activity, Patient Compliance, Practice Guidelines as Topic, Risk, United States|
AIMS: Analyze relationships between adherence to guidelines for diabetes care - regular screening; physical activity; and medication - and diabetes complications and mortality.
METHODS: Outcomes were onset of congestive heart failure (CHF), stroke, renal failure, moderate complications of lower extremities, lower-limb amputation, proliferative diabetic retinopathy (PDR), and mortality during follow-up. Participants were persons aged 65+ in the Health and Retirement Study (HRS) 2003 Diabetes Study and had Medicare claims in follow-up period (2004-8).
RESULTS: Adherence to screening recommendations decreased risks of developing CHF (odds ratio (OR)=0.83; 95% confidence interval (CI): 0.72-0.96), stroke (OR=0.80; 95% CI: 0.68-0.94); renal failure (OR=0. 82; 95% CI: 0.71-0.95); and death (OR=0.86; 95% CI: 0.74-0.99). Adherence to physical activity recommendation reduced risks of stroke (OR=0.64; 95% CI: 0.45-0.90), renal failure (OR=0.71; 95% CI: 0.52-0.97), moderate lower-extremity complications (OR=0.71; 95% CI: 0.51-0.99), having a lower limb amputation (OR=0.31, 95% CI: 0.11-0.85), and death (OR=0.56, 95% CI: 0.41-0.77). Medication adherence was associated with lower risks of PDR (OR=0.35, 95% CI: 0.13-0.93).
CONCLUSIONS: Adherence to screening, physical activity and medication guidelines was associated with lower risks of diabetes complications and death. Relative importance of adherence differed among outcome measures.
|User Guide Notes|
|Endnote Keywords|| |
Diabetes complications/Mortality/health status/adherence interventions/adherence interventions/Physical activity/Guidelines
|Endnote ID|| |
|Alternate Journal||J. Diabetes Complicat.|
|PubMed Central ID||PMC4656150|
|Grant List||R01 AG017473 / AG / NIA NIH HHS / United States |
R01-AG017473 / AG / NIA NIH HHS / United States