|Title||The link between discrimination and telomere length in African American adults.|
|Publication Type||Journal Article|
|Year of Publication||2017|
|Authors||Lee, DB, Kim, ES, Neblett, EW|
|Date Published||2017 May|
|Keywords||Discrimination, Racial/ethnic differences, Telomeres, Women and Minorities|
OBJECTIVE: Prior work shows that discrimination is associated with a wide array of negative health outcomes. However, the biological mechanisms through which this link occurs require more study. We evaluated the association between discrimination and leukocyte telomere length (LTL; a biological marker of systemic aging).
METHOD: Cross-sectional data were from the Health and Retirement study, a study of people aged 51+ in the United States, and included 595 African American males and females. Multiple regression analyses were used to evaluate whether discrimination was independently associated with LTL. We also considered the role of potential confounders including sociodemographic factors, health factors, depressive symptoms, and stress.
RESULTS: High discrimination was associated with shorter LTL after controlling for sociodemographic factors (b = -.034, SE = 0.14, p = .017). This association persisted in analyses that further adjusted for health factors, depressive symptoms, and stress.
CONCLUSION: Results suggest that discrimination experiences accelerate biological aging in older African American males and females, alike. This finding helps advance our understanding of how discrimination generates greater disease vulnerability and premature death in African Americans. (PsycINFO Database Record
|User Guide Notes|
|Alternate Journal||Health Psychol|
|Grant List||T32 HD079350 / HD / NICHD NIH HHS / United States |
P01 CA087969 / CA / NCI NIH HHS / United States
UM1 CA186107 / CA / NCI NIH HHS / United States
T32 HL098048 / HL / NHLBI NIH HHS / United States