|Title||Neuroprotective diets are associated with better cognitive function: The Health and Retirement Study.|
|Publication Type||Journal Article|
|Year of Publication||2017|
|Authors||McEvoy, CT, Guyer, HM, Langa, KM, Yaffe, K|
|Journal||Journal of the American Geriatrics Society|
|Keywords||Cognitive Ability, Eating habits|
OBJECTIVES: To evaluate the association between the Mediterranean diet (MedDiet) and the Mediterranean-DASH diet Intervention for Neurodegeneration Delay (MIND diet) and cognition in a nationally representative population of older U.S. adults.
DESIGN: Population-based cross-sectional study.
SETTING: Health and Retirement Study.
PARTICIPANTS: Community-dwelling older adults (N = 5,907; mean age 67.8 ± 10.8).
MEASUREMENTS: Adherence to dietary patterns was determined from food frequency questionnaires using criteria determined a priori to generate diet scores for the MedDiet (range 0-55) and MIND diet (range 0-15). Cognitive performance was measured using a composite test score of global cognitive function (range 0-27). Linear regression was used to compare cognitive performance according to tertiles of dietary pattern. Logistic regression was used to examine the association between dietary patterns and clinically significant cognitive impairment. Models were adjusted for age, sex, race, educational attainment, and other health and lifestyle covariates.
RESULTS: Participants with mid (odds ratio (OR) = 0.85, 95% confidence interval (CI) = 0.71-1.02, P = .08) and high (OR 0.65, 95% CI = 0.52-0.81, P < .001) MedDiet scores were less likely to have poor cognitive performance than those with low scores in fully adjusted models. Results for the MIND diet were similar. Higher scores in each dietary pattern were independently associated with significantly better cognitive function (P < .001) in a dose-response manner (P trend < .001).
CONCLUSION: In a large nationally representative population of older adults, greater adherence to the MedDiet and MIND diet was independently associated with better cognitive function and lower risk of cognitive impairment. Clinical trials are required to elucidate the role of dietary patterns in cognitive aging.
|User Guide Notes|
|Alternate Journal||J Am Geriatr Soc|
|PubMed Central ID||PMC5633651|
|Grant List||P30 AG053760 / AG / NIA NIH HHS / United States |
U01 AG009740 / AG / NIA NIH HHS / United States
K08 AG019180 / AG / NIA NIH HHS / United States
P30 AG024824 / AG / NIA NIH HHS / United States
K24 AG031155 / AG / NIA NIH HHS / United States
R01 AG027010 / AG / NIA NIH HHS / United States
/ / Wellcome Trust / United Kingdom
RF1 AG055273 / AG / NIA NIH HHS / United States