Neighborhoods, sleep quality, and cognitive decline: Does where you live and how well you sleep matter?

TitleNeighborhoods, sleep quality, and cognitive decline: Does where you live and how well you sleep matter?
Publication TypeJournal Article
Year of Publication2018
AuthorsHunter, JC, Handing, EP, Casanova, R, Kuchibhatla, M, Lutz, MW, Saldana, S, Plassman, BL, Hayden, KM
JournalAlzheimer's & Dementia
Volume14
Issue4
Pagination454-461
ISSN Number15525260
KeywordsCognitive Ability, Neighborhoods, Sleep, Socioeconomic factors
Abstract

Introduction
We evaluated the association between neighborhood socioeconomic status (NSES) and sleep quality on cognitive decline in the Health and Retirement Study.

Methods
Health and Retirement Study participants (n = 8090), aged 65+ with DNA and multiple biennial cognitive observations (abbreviated Telephone Interview for Cognitive Status), were included. Participants were grouped into quartiles of NSES and sleep quality scores. We adjusted for apolipoprotein E ε4, demographic, and cardiovascular risk factors. Random effects modeling evaluated cognitive change over time.

Results
NSES and sleep were significantly associated with cognitive decline, and there was a significant interaction between them (P = .02). Significant differences between high/low NSES and high/low sleep quality (P < .0001) were found.

Discussion
Sleep and NSES were associated with cognitive decline; the association between sleep and cognition appeared stronger among those with low NSES. The association between low NSES, poor sleep quality, and cognitive decline was roughly equivalent to the association between apolipoprotein E ε4 and cognitive decline.

URLhttps://www.sciencedirect.com/science/article/pii/S1552526017338086
DOI10.1016/j.jalz.2017.10.007
Short TitleAlzheimer's & Dementia
Citation Key9481
PubMed ID29396109
PubMed Central IDPMC5899662