Title | The Sociogenomics of Polygenic Scores of Reproductive Behavior and Their Relationship to Other Fertility Traits |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Mills, MC, Barban, N, Tropf, FC |
Journal | RSF: The Russell Sage Foundation Journal of the Social Sciences |
Volume | 4 |
Issue | 4 |
Pagination | 122-136 |
Date Published | Jan-01-2018 |
ISSN Number | 23778253 |
Keywords | Education, Fertility, Genetics, GWAS, PGS |
Abstract | Human reproductive behavior until relatively recently has been explained exclusively via individual and social characteristics. This article applies results from a recent Genome-Wide Association Study that combined sixty-two data sources to isolate twelve genetic loci associated with reproductive behavior. We create polygenic scores that allow us to include a summary variable of genetic factors into our statistical models. We use four datasets: the U.S. Health and Retirement Study, Dutch LifeLines, TwinsUK and the Swedish Twin register. First, we provide a brief overview of the dominant explanations of reproductive behavior. Second, we test the predictive power of polygenic scores. Third, we interrogate the robustness of our models using a series of sensitivity analyses to take into account possible confounders due to population stratification and selection. |
URL | http://www.jstor.org/stable/10.7758/rsf.2018.4.4.07 |
DOI | 10.7758/rsf.2018.4.4.07 |
Short Title | RSF: The Russell Sage Foundation Journal of the Social Sciences |
Citation Key | 9912 |