|Title||The Sociogenomics of Polygenic Scores of Reproductive Behavior and Their Relationship to Other Fertility Traits|
|Publication Type||Journal Article|
|Year of Publication||2018|
|Authors||Mills, MC, Barban, N, Tropf, FC|
|Journal||RSF: The Russell Sage Foundation Journal of the Social Sciences|
|Keywords||Education, Fertility, Genetics, GWAS, PGS|
Human reproductive behavior until relatively recently has been explained exclusively via individual and social characteristics. This article applies results from a recent Genome-Wide Association Study that combined sixty-two data sources to isolate twelve genetic loci associated with reproductive behavior. We create polygenic scores that allow us to include a summary variable of genetic factors into our statistical models. We use four datasets: the U.S. Health and Retirement Study, Dutch LifeLines, TwinsUK and the Swedish Twin register. First, we provide a brief overview of the dominant explanations of reproductive behavior. Second, we test the predictive power of polygenic scores. Third, we interrogate the robustness of our models using a series of sensitivity analyses to take into account possible confounders due to population stratification and selection.
|Short Title||RSF: The Russell Sage Foundation Journal of the Social Sciences|