HRS Bibliography

Search Filters

Author: Eric Klopack

Displaying 1 - 25 of 28

2026

How epigenetic clocks tick: Unpacking the black box by deciphering biological pathways and transcriptomic signatures of accelerated aging.

Thalida Arpawong, Steve Cole, Harshanna Badhesha, Jung Kim, Christopher Beam, Eric Klopack, Kimberly Siegmund, Bharat Thyagarajan, Eileen Crimmins

Research square, 2026

Epigenetic g predicts cognitive function in a diverse, nationally representative sample of older adults.

Jessica Faul, Stacey Collins, Trey Smith, Eric Klopack, Colter Mitchell, Eileen Crimmins, Mateo Farina

Clinical epigenetics, 2026

An ageing biomarker signature predicts chronic disease cluster trajectories, physical function and mortality: validation in the TILDA and HRS cohorts.

Belinda Hernandez, Eric Klopack, Frank Moriarty, Padraic Fallon, Nollaig Bourke, Eileen Crimmins, Rose-Anne Kenny, Cathal Crory, Aisling O'Halloran

Age and ageing, 2026

Biomarkers help us understand how cellular and systemic aging contribute to mortality: A study utilizing a machine learning approach in the Health and Retirement Study.

Eric Klopack, Eileen Crimmins

J Gerontol A Biol Sci Med Sci, 2026

2025

A novel DNA methylation-based surrogate biomarker for chronic systemic inflammation (Inflammation Latent Variable Methylation Surrogate, InfLaMeS).

Helen Meier, Eric Klopack, Mateo Farnia, Belinda Hernandez, Colter Mitchell, Jessica Faul, Cathal McCrory, Rose Kenny, Eileen Crimmins

The journals of gerontology. Series A, Biological sciences and medical sciences, 2025

How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study.

Eric Klopack, Mateo Farina, Bharat Thyagarajan, Jessica Faul, Eileen Crimmins

J Alzheimers Dis, 2025

Using machine-learning to identify differences in the association between blood-based biomarkers and later life health across race and ethnicity.

Mateo Farina, Eric Klopack, Eileen Crimmins

J Gerontol A Biol Sci Med Sci, 2025

Gene expression composite scores of cellular senescence predict aging health outcomes in the Health and Retirement Study.

Qiao Wu, Eric Klopack, Jung Kim, Em Arpawong, Bharat Thyagarajan, Steve Cole, Jessica Faul, Fengxue Zhou, Eileen Crimmins

Nat Commun, 2025

Physiological health Age (PhysAge): a novel multi-system molecular timepiece predicts health and mortality in older adults.

Em Arpawong, Belinda Hernandez, Claire Potter, Robert Leigh, Eric Klopack, Claire Hill, Giovanni Fiorito, Laura Smyth, Aisling O'Halloran, Bernadette McGuinness, Jessica Faul, Rose Kenny, Amy McKnight, Eileen Crimmins, Cathal McCrory

Geroscience, 2025

How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study.

Eric Klopack, Mateo Farina, Bharat Thyagarajan, Jessica Faul, Eileen Crimmins

Journal of Alzheimer's disease : JAD, 2025

2024

The embodiment of parental death in early life through accelerated epigenetic aging: Implications for understanding how parental death before 18 shapes age-related health risk among older adults

Mateo Farina, Eric Klopack, Debra Umberson, Eileen Crimmins

SSM - Population Health, 2024

Generations of epigenetic clocks and their links to socioeconomic status in the Health and Retirement Study.

Eileen Crimmins, Eric Klopack, Jung Kim

Epigenomics, 2024

Epigenetic Aging Helps Explain Differential Resilience in Older Adults.

Eric Klopack, Eileen Crimmins

Demography, 2024

RNA-based Indicators of Cellular Senescence Predict Aging Health Outcomes in the Health and Retirement Study

Qiao Wu, Eric Klopack, Jung Kim, Thalida Arpawong, Bharat Thyagarajan, Steve Cole, Jessica Faul, Fengxue Zhou, Eileen Crimmins

2024

Short sleep and insomnia are associated with accelerated epigenetic age.

Cynthia Kusters, Eric Klopack, Eileen Crimmins, Teresa Seeman, Steve Cole, Judith Carroll

Psychosom Med, 2024

2023

Social relationships and epigenetic aging in older adulthood: Results from the Health and Retirement Study.

Kelly Rentscher, Eric Klopack, Eileen Crimmins, Teresa Seeman, Steve Cole, Judith Carroll

Brain, behavior and immunity, 2023

Parental Divorce in Childhood and the Accelerated Epigenetic Aging for Earlier and Later Cohorts: Role of Mediators of Chronic Depressive Symptoms, Education, Smoking, Obesity, and Own Marital Disruption

Jung Kim, Em Arpawong, Eric Klopack, Eileen Crimmins

Journal of Population Ageing, 2023

Immune cells are associated with mortality: the Health and Retirement Study.

Gokul Seshadri, Sithara Vivek, Anna Prizment, Eileen Crimmins, Eric Klopack, Jessica Faul, Weihua Guan, Helen Meier, Bharat Thyagarajan

Frontiers in immunology, 2023

ADHD genetic burden associates with older epigenetic age: mediating roles of education, behavioral and sociodemographic factors among older adults.

Thalida Arpawong, Eric Klopack, Jung Kim, Eileen Crimmins

Clin Epigenetics, 2023

Chronic Stress and Latent Virus Reactivation: Effects on Immune Aging, Chronic Disease Morbidity, and Mortality.

Eric Klopack

J Gerontol B Psychol Sci Soc Sci, 2023

2022

Socioeconomic status and immune aging in older US adults in the health and retirement study.

Eric Klopack, Bharat Thyagarajan, Jessica Faul, Helen Meier, Ramya Ramasubramanian, Jung Kim, Eileen Crimmins

Biodemography and Social Biology, 2022

How stress may accelerate aging of the immune system

Eric Klopack

The Washington Post, 2022

Google Scholar

Accelerated epigenetic aging mediates link between adverse childhood experiences and depressive symptoms in older adults: Results from the Health and Retirement Study.

Eric Klopack, Eileen Crimmins, Steve Cole, Teresa Seeman, Judith Carroll

SSM Population Health, 2022

Social stressors associated with age-related T lymphocyte percentages in older US adults: Evidence from the US Health and Retirement Study.

Eric Klopack, Eileen Crimmins, Steve Cole, Teresa Seeman, Judith Carroll

Proceedings of the National Academy of Sciences, 2022

Lifetime exposure to smoking, epigenetic aging, and morbidity and mortality in older adults.

Eric Klopack, Judith Carroll, Steve Cole, Teresa Seeman, Eileen Crimmins

Clinical Epigenetics, 2022