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2026

Biomarkers help us understand how cellular and systemic aging contribute to mortality: A study utilizing a machine learning approach in the Health and Retirement Study.

Eric Klopack, Eileen Crimmins

J Gerontol A Biol Sci Med Sci, 2026

2025

How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study.

Eric Klopack, Mateo Farina, Bharat Thyagarajan, Jessica Faul, Eileen Crimmins

J Alzheimers Dis, 2025

Using machine-learning to identify differences in the association between blood-based biomarkers and later life health across race and ethnicity.

Mateo Farina, Eric Klopack, Eileen Crimmins

J Gerontol A Biol Sci Med Sci, 2025

How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study.

Eric Klopack, Mateo Farina, Bharat Thyagarajan, Jessica Faul, Eileen Crimmins

Journal of Alzheimer's disease : JAD, 2025

A novel DNA methylation-based surrogate biomarker for chronic systemic inflammation (Inflammation Latent Variable Methylation Surrogate, InfLaMeS).

Helen Meier, Eric Klopack, Mateo Farnia, Belinda Hernandez, Colter Mitchell, Jessica Faul, Cathal McCrory, Rose Kenny, Eileen Crimmins

The journals of gerontology. Series A, Biological sciences and medical sciences, 2025

2024

Epigenetic Aging Helps Explain Differential Resilience in Older Adults.

Eric Klopack, Eileen Crimmins

Demography, 2024

Short sleep and insomnia are associated with accelerated epigenetic age.

Cynthia Kusters, Eric Klopack, Eileen Crimmins, Teresa Seeman, Steve Cole, Judith Carroll

Psychosom Med, 2024

Generations of epigenetic clocks and their links to socioeconomic status in the Health and Retirement Study.

Eileen Crimmins, Eric Klopack, Jung Kim

Epigenomics, 2024

2023

ADHD genetic burden associates with older epigenetic age: mediating roles of education, behavioral and sociodemographic factors among older adults.

Thalida Arpawong, Eric Klopack, Jung Kim, Eileen Crimmins

Clin Epigenetics, 2023

Chronic Stress and Latent Virus Reactivation: Effects on Immune Aging, Chronic Disease Morbidity, and Mortality.

J Gerontol B Psychol Sci Soc Sci, 2023

Social relationships and epigenetic aging in older adulthood: Results from the Health and Retirement Study.

Kelly Rentscher, Eric Klopack, Eileen Crimmins, Teresa Seeman, Steve Cole, Judith Carroll

Brain, behavior and immunity, 2023

2022

Accelerated epigenetic aging mediates link between adverse childhood experiences and depressive symptoms in older adults: Results from the Health and Retirement Study.

Eric Klopack, Eileen Crimmins, Steve Cole, Teresa Seeman, Judith Carroll

SSM Population Health, 2022

Social stressors associated with age-related T lymphocyte percentages in older US adults: Evidence from the US Health and Retirement Study.

Eric Klopack, Eileen Crimmins, Steve Cole, Teresa Seeman, Judith Carroll

Proceedings of the National Academy of Sciences, 2022

Lifetime exposure to smoking, epigenetic aging, and morbidity and mortality in older adults.

Eric Klopack, Judith Carroll, Steve Cole, Teresa Seeman, Eileen Crimmins

Clinical Epigenetics, 2022

How stress may accelerate aging of the immune system

The Washington Post, 2022

Google Scholar

Socioeconomic status and immune aging in older US adults in the health and retirement study.

Eric Klopack, Bharat Thyagarajan, Jessica Faul, Helen Meier, Ramya Ramasubramanian, Jung Kim, Eileen Crimmins

Biodemography and Social Biology, 2022

Forthcoming

Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA).

Eric Klopack, Gokul Seshadri, Em Arpawong, Steve Cole, Bharat Thyagarajan, Eileen Crimmins

medRxiv, Forthcoming

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